6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID
6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID
CAS: 33458-93-4
Molecular Formula: C17H14O5
6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID - Names and Identifiers
6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID - Physico-chemical Properties
| Molecular Formula | C17H14O5 |
| Molar Mass | 298.29 |
| Solubility | ethanol: 2.5mg/mL, soluble |
| Appearance | crystalline solid or supercooled liquid |
| Color | White |
| Storage Condition | Sealed in dry,Room Temperature |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 6 months. |
| In vitro study | AH 6809 (1 μM; 30 min) inhibits T. serrulatus venom (TsV)-induced and PGE 2 -amplified IL-1β and cAMP production in macrophages. AH 6809 (30-300 μM) antagonizes the anti-aggregatory activity of PGD2 in whole blood, with an apparent pA 2 of 5.35. |
| In vivo study | AH 6809 (5 mg/kg; i.p.) decreases TsV-induced mortality, PGE 2 and IL-1β production and neutrophil infiltration in the lungs of mice. |
6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID - Risk and Safety
| WGK Germany | 3 |
6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.352 ml | 16.762 ml | 33.524 ml |
| 5 mM | 0.67 ml | 3.352 ml | 6.705 ml |
| 10 mM | 0.335 ml | 1.676 ml | 3.352 ml |
| 5 mM | 0.067 ml | 0.335 ml | 0.67 ml |
Last Update：2024-01-02 23:10:35
6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID - Reference Information
| biological activity | AH 6809 is an antagonist of EP and DP receptors. the Ki values for cloned human EP1,EP2,EP3-III and DP receptors are 1217, 1150, 1597 and 1415 nM respectively, and the Ki values for mouse EP2 receptors are 350 nM. |
| target | h-EP 1 receptor 1217 nM (Ki) h-EP 2 receptor 1150 nM (Ki) h-EP 3 -III receptor 1597 nM (Ki) m-EP 2 receptor 350 nM (Ki) hDP Receptor 1415 nM (Ki) |
| in vitro study | AH 6809 (1 μM; 30 min) inhibits T. serrulatus venom (TsV)-induced and PGE 2 -amplified IL-1β and cAMP production in macrophages. AH 6809 (30-300 μM) antagonizes the anti-aggregatory activity of PGD2 in whole blood, with an apparent pA 2 of 5.35. |
| in vivo study | AH 6809 (5 mg/kg; I. p.) decreases TsV-induced mortality, PGE 2 and IL-1β production and neutrophil infiltration in the lungs of mice. |
Last Update：2024-04-09 20:52:54
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CAS: 33458-93-4
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CAS: 33458-93-4
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Product Name: 6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID Visit Supplier Webpage Request for quotation
CAS: 33458-93-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 33458-93-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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